GL1X · GenesisL1 explorer

Ligand · VVQ

VVQ · 5-(2-aminopyrimidin-4-yl)-2-(5-chloro-2-methylphenyl)-1H-pyrrole-3-carboxamide

VVQ, 5-(2-aminopyrimidin-4-yl)-2-(5-chloro-2-methylphenyl)-1H-pyrrole-3-carboxamide (C16 H14 Cl N5 O, 327.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component
VVQ
Formula
C16 H14 Cl N5 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

VVQ in 2 structures; the first of them:

  • 4D0W · Pyrrole-3-carboxamides as potent and selective JAK2 inhibitors · VVQ A2132 · binds LEU855, GLY856, LYS857, GLY858, GLY861, SER862, VAL863, ALA880 and 12 more
  • 4D0W · Pyrrole-3-carboxamides as potent and selective JAK2 inhibitors · VVQ A2132 · binds LEU855, GLY856, LYS857, GLY858, GLY861, SER862, VAL863, ALA880 and 12 more

Residues it binds most

GLY 2, LEU 2, ASP 2, SER 2, VAL 2, ALA 2, ARG 2, ASN 2, GLU 2, LYS 2 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.