Ligand · VOY

VOY · (2E)-N-[3-cyano-7-ethoxy-4-({3-methyl-4-[([1,2, 4]triazolo[1,5-a]pyridin-7-yl)oxy]phenyl}amino) quinolin-6-yl]-4-(dimethylamino)but-2-enamide

VOY, (2E)-N-[3-cyano-7-ethoxy-4-({3-methyl-4-[([1,2, 4]triazolo[1,5-a]pyridin-7-yl)oxy]phenyl}amino) quinolin-6-yl]-4-(dimethylamino)but-2-enamide (C31 H30 N8 O3, 562.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1…

Component: VOY
Formula: C31 H30 N8 O3
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

VOY in 2 structures; the first of them:

7JXH · HER2 in complex with JBJ-08-178-01 · VOY B1101 · binds LEU726, VAL734, ALA751, ILE752, LYS753, MET774, SER783, ARG784 and 18 more
7JXH · HER2 in complex with jbj-08-178-01 · VOY B1101 · binds LEU726, VAL734, ALA751, LYS753, MET774, SER783, LEU785, LEU796 and 11 more

Residues it binds most

LEU 16, MET 16, THR 16, ASP 16, ARG 14, LYS 16, ALA 16, CYS 16, GLY 16, SER 16 (residue and the binding sites it lines).

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