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Ligand · VM8

VM8 · 5-(2-methyl-1-phenyl-propan-2-yl)imidazo[2,1-a]isoquinoline

VM8, 5-(2-methyl-1-phenyl-propan-2-yl)imidazo[2,1-a]isoquinoline (C21 H20 N2, 300.4 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
VM8
Formula
C21 H20 N2
Class
ligand
Structures
1
PDB entries
1

Binding sites

VM8 in 1 structure; the first of them:

  • 8OG8 · Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 3 · VM8 A1501 · binds THR1097, CYS1098, ILE1138, THR1139, HIS1140, TYR1181, ARG1225, CYS1227 and 9 more

Residues it binds most

ARG 2, LEU 2, MET 2, PHE 2, CYS 1, ILE 1, LYS 2, SER 1, THR 1, TYR 2 (residue and the binding sites it lines).

Found with

  • ACT · Acetate ion
  • EDO · 1,2-ethanediol

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