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Ligand · VJZ

VJZ · 5-[4-(1,5-dimethylpyrazol-4-yl)-2-methyl-phenyl]-~{N}-(imidazo[1,2-a]pyridin-6-ylmethyl)-~{N}-methyl-1,3,4-oxadiazol-2-amine

VJZ, 5-[4-(1,5-dimethylpyrazol-4-yl)-2-methyl-phenyl]-~{N}-(imidazo[1,2-a]pyridin-6-ylmethyl)-~{N}-methyl-1,3,4-oxadiazol-2-amine (C23 H23 N7 O, 413.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
VJZ
Formula
C23 H23 N7 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

VJZ in 2 structures; the first of them:

  • 7OLS · MerTK kinase domain with type 1.5 inhibitor containing a di-methyl pyrazole group · VJZ A901 · binds LEU593, VAL601, ALA617, LYS619, PHE634, GLU637, ALA638, MET641 and 11 more
  • 7OLS · Mertk kinase domain with type 1.5 inhibitor containing a di-methyl pyrazole group · VJZ A901 · binds VAL601, ALA617, PHE634, GLU637, ALA638, MET641, ILE650, LEU652 and 9 more

Residues it binds most

ALA 2, MET 2, PHE 2, LEU 2, VAL 2, ASP 2, GLU 2, ILE 2, PRO 2, LYS 1 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion
  • DMS · Dimethyl sulfoxide

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