Ligand · VJN
VJN · 8-propan-2-yloxy-4~{H}-thieno[2,3-c]isoquinolin-5-one
VJN, 8-propan-2-yloxy-4~{H}-thieno[2,3-c]isoquinolin-5-one (C14 H13 N O2 S, 259.3 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds…
- Component
- VJN
- Formula
- C14 H13 N O2 S
- Class
- ligand
- Structures
- 4
- PDB entries
- 3
Binding sites
VJN in 4 structures; the first of them:
- 7OLJ · Tankyrase 2 in complex with an inhibitor (OUL219) · VJN AAA1201 · binds PHE1030, HIS1031, GLY1032, TYR1050, MET1054, PHE1055, TYR1060, PHE1061 and 6 more
- 7OMC · Tankyrase 2 in complex with an inhibitor (OUL228) · VJN AAA1201 · binds PHE1030, HIS1031, GLY1032, TYR1050, MET1054, PHE1055, TYR1060, PHE1061 and 5 more
- 7OTH · PARP15 catalytic domain in complex with OUL219 · VJN A701 · binds PHE558, HIS559, GLY560, ALA583, TYR591, ALA593, TYR598, SER599 and 2 more
- 7OTH · PARP15 catalytic domain in complex with OUL219 · VJN A701 · binds PHE558, HIS559, GLY560, ALA583, TYR591, TYR598, SER599, TYR604 and 1 more
Residues it binds most
TYR 6, PHE 6, ALA 6, GLY 6, HIS 6, SER 6, GLU 4, LYS 4, MET 4, ILE 3 (residue and the binding sites it lines).
Found with
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