GL1X · GenesisL1 explorer

Ligand · VGS

VGS · 2,2-dimethyl-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl) propanamide

VGS, 2,2-dimethyl-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl) propanamide (C7 H12 N4 O3 S2, 264.3 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues…

Component
VGS
Formula
C7 H12 N4 O3 S2
Class
ligand
Structures
4
PDB entries
2

Binding sites

VGS in 4 structures; the first of them:

  • 7JNX · Carbonic Anhydrase II Complexed with N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)pivalamide · VGS A303 · binds ILE91, GLN92, HIS94, HIS96, GLU106, HIS119, VAL121, PHE131 and 7 more
  • 7JO3 · Carbonic Anhydrase IX Mimic Complexed with N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)pivalamide · VGS A302 · binds LEU91, GLN92, HIS94, HIS96, GLU106, HIS119, VAL121, VAL131 and 7 more
  • 7JNX · Carbonic anhydrase II complexed with N-(5-sulfamoyl-1,3,4-thiadiazol- 2-YL)PIVALAMIDE · VGS A303 · binds ILE91, GLN92, HIS94, HIS96, GLU106, HIS119, VAL121, PHE131 and 7 more
  • 7JO3 · Carbonic anhydrase IX mimic complexed with N-(5-sulfamoyl-1,3,4… · VGS A302 · binds LEU91, GLN92, HIS94, HIS96, GLU106, HIS119, VAL121, VAL131 and 7 more

Residues it binds most

VAL 4, HIS 4, THR 4, LEU 4, GLN 4, GLU 4, SER 4, TRP 4, ILE 2, PHE 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • DMS · Dimethyl sulfoxide
  • GOL · Glycerol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.