GL1X · GenesisL1 explorer

Ligand · VG5

VG5 · N-[(1S,2R)-1-benzyl-3-{[(1S)-2-(cyclohexylamino)-1-methyl-2-oxoethyl]amino}-2-hydroxypropyl]-3-(ethylamino)-5-(2-oxopyrrolidin-1-yl)benzamide

VG5, N-[(1S,2R)-1-benzyl-3-{[(1S)-2-(cyclohexylamino)-1-methyl-2-oxoethyl]amino}-2-hydroxypropyl]-3-(ethylamino)-5-(2-oxopyrrolidin-1-yl)benzamide (C32 H45 N5 O4, 563.7 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2…

Component
VG5
Formula
C32 H45 N5 O4
Class
ligand
Structures
4
PDB entries
2

Binding sites

VG5 in 4 structures; the first of them:

  • 2VJ6 · Human BACE-1 in complex with N-((1S,2R)-3-(((1S)-2-(cyclohexylamino)… · VG5 A1447 · binds SER71, GLY72, GLN73, GLY74, LEU91, ASP93, GLY95, SER96 and 20 more
  • 2XFJ · Human BACE-1 in complex with N-((1S,2R)-3-(((1S)-2-(cyclohexylamino)… · VG5 A500 · binds GLY72, GLN73, GLY74, LEU91, ASP93, GLY95, SER96, VAL130 and 19 more
  • 2VJ6 · Human bace-1 in complex with N-((1S,2R)-3-(((1S)-2-(cyclohexylamino)… · VG5 A1447 · binds SER71, GLY72, GLN73, GLY74, LEU91, ASP93, GLY95, SER96 and 20 more
  • 2XFJ · Human bace-1 in complex with N-((1S,2R)-3-(((1S)-2-(cyclohexylamino)… · VG5 A500 · binds GLY72, GLN73, GLY74, LEU91, ASP93, GLY95, SER96, VAL130 and 19 more

Residues it binds most

GLY 4, ILE 4, THR 4, SER 4, ARG 4, ASP 4, GLN 4, TYR 4, ASN 4, LEU 4 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.