Ligand · VFC
VFC · N-[(2R)-1-(3-cyanoazetidin-1-yl)-1-oxidanylidene-propan-2-yl]-2-(6-fluoranyl-1-methyl-indazol-3-yl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide
VFC, N-[(2R)-1-(3-cyanoazetidin-1-yl)-1-oxidanylidene-propan-2-yl]-2-(6-fluoranyl-1-methyl-indazol-3-yl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide (C22 H19 F N8 O2, 446.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1…
- Component
- VFC
- Formula
- C22 H19 F N8 O2
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
VFC in 2 structures; the first of them:
- 3ZC6 · Crystal structure of JAK3 kinase domain in complex with an indazole substituted… · VFC A2103 · binds LEU828, GLY829, LYS830, GLY831, GLY834, SER835, VAL836, ALA853 and 15 more
- 3ZC6 · Crystal structure of JAK3 kinase domain in complex with an indazole substituted… · VFC A2103 · binds LEU828, GLY829, LYS830, GLY831, GLY834, SER835, VAL836, ALA853 and 15 more
Residues it binds most
GLY 8, LEU 8, ALA 8, ARG 8, ASP 8, LYS 8, VAL 8, ASN 8, CYS 8, GLU 8 (residue and the binding sites it lines).
Found with
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