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Ligand · VEK

VEK · 6-bromo-2-(1-methyl-1H-imidazol-5-yl)-7-{4-[(5-methyl-1,2-oxazol-3-yl)methyl]piperazin-1-yl}-1H-imidazo[4,5-b]pyridine

VEK, 6-bromo-2-(1-methyl-1H-imidazol-5-yl)-7-{4-[(5-methyl-1,2-oxazol-3-yl)methyl]piperazin-1-yl}-1H-imidazo[4,5-b]pyridine (C19 H21 Br N8 O, 457.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
VEK
Formula
C19 H21 Br N8 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

VEK in 2 structures; the first of them:

  • 4B0G · Complex of Aurora-A bound to an Imidazopyridine-based inhibitor · VEK A1392 · binds ARG137, LEU139, GLY140, LYS141, GLY142, LYS143, GLY145, ASN146 and 12 more
  • 4B0G · Complex of aurora-a bound to an imidazopyridine-based inhibitor · VEK A1392 · binds ARG137, LEU139, GLY140, LYS141, GLY142, LYS143, GLY145, ASN146 and 12 more

Residues it binds most

GLY 2, LEU 2, LYS 2, ALA 2, ARG 2, ASN 2, GLU 2, PRO 2, THR 2, TYR 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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