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Ligand · VCG

VCG · 2-hydroxyethyl 2-deoxy-3,5-bis-O-(2-hydroxyethyl)-6-O-(2-{[(9E)-octadec-9-enoyl]oxy}ethyl)-alpha-L-xylo-hexofuranoside

VCG, 2-hydroxyethyl 2-deoxy-3,5-bis-O-(2-hydroxyethyl)-6-O-(2-{[(9E)-octadec-9-enoyl]oxy}ethyl)-alpha-L-xylo-hexofuranoside (C32 H60 O10, 604.8 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every…

Component
VCG
Formula
C32 H60 O10
Class
ligand
Structures
4
PDB entries
2

Binding sites

VCG in 4 structures; the first of them:

  • 7E7B · Cryo-EM structure of the SARS-CoV-2 furin site mutant S-Trimer from a subunit vaccine… · VCG A1608 · binds ILE101, TRP104, ILE119, ASN121, VAL126, ILE128, PHE168, TYR170 and 14 more
  • 7JJI · Structure of SARS-CoV-2 3Q-2P full-length prefusion spike trimer (C3 symmetry) · VCG A1302 · binds ILE101, ARG102, GLY103, TRP104, ILE119, ASN121, VAL126, ILE128 and 9 more
  • 7E7B · Cryo-EM structure of the SARS-cov-2 furin site mutant S-trimer from a subunit vaccine… · VCG A1608 · binds ILE101, TRP104, ILE119, ASN121, VAL126, ILE128, PHE168, TYR170 and 14 more
  • 7JJI · Structure of SARS-cov-2 3Q-2P full-length prefusion spike trimer (C3 symmetry) · VCG A1302 · binds ILE101, ARG102, GLY103, TRP104, ILE119, ASN121, VAL126, ILE128 and 9 more

Residues it binds most

ILE 12, ARG 12, PHE 12, LEU 12, VAL 12, TYR 12, ASN 12, SER 12, TRP 12, GLY 6 (residue and the binding sites it lines).

Found with

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • EIC · Linoleic acid
  • ELA · 9-octadecenoic acid

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