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Ligand · VAQ

VAQ · 4-[[(3S)-3-cyclopropyl-2-azaspiro[3.3]heptan-2-yl]methyl]-2-oxidanyl-N-[[(3R)-3-oxidanyl-1-[6-[(phenylmethyl)amino]pyrimidin-4-yl]piperidin-3-yl]methyl]benzamide

VAQ, 4-[[(3S)-3-cyclopropyl-2-azaspiro[3.3]heptan-2-yl]methyl]-2-oxidanyl-N-[[(3R)-3-oxidanyl-1-[6-[(phenylmethyl)amino]pyrimidin-4-yl]piperidin-3-yl]methyl]benzamide (C34 H42 N6 O3, 582.8 g/mol), in the MolNFT structures on GenesisL1…

Component
VAQ
Formula
C34 H42 N6 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

VAQ in 2 structures; the first of them:

  • 7OEK · Crystal structure of the human METTL3-METTL14 complex with compound UOZ091 · VAQ A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, PRO396, PRO397, TYR406 and 18 more
  • 7OEK · Crystal structure of the human METTL3-METTL14 complex with compound UOZ091 · VAQ A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, PRO396, PRO397, TYR406 and 18 more

Residues it binds most

GLY 2, ARG 2, ASP 2, HIS 2, PRO 2, THR 2, TRP 2, ASN 2, CYS 2, GLN 2 (residue and the binding sites it lines).

Found with

  • ACT · Acetate ion

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