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Ligand · V81

V81 · 5-[2-amino-3-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-2-[(1S)-1-cyclopropylethyl]-7-(trifluoromethyl)-2,3-dihydro-1H-isoindol-1-one

V81, 5-[2-amino-3-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-2-[(1S)-1-cyclopropylethyl]-7-(trifluoromethyl)-2,3-dihydro-1H-isoindol-1-one (C24 H22 F3 N7 O, 481.5 g/mol), in the MolNFT structures on GenesisL1: bound in 1…

Component
V81
Formula
C24 H22 F3 N7 O
Class
ligand
Structures
1
PDB entries
1

Binding sites

V81 in 1 structure; the first of them:

  • 6XRM · Crystal structure of human PI3K-gamma in complex with compound 4 · V81 A1101 · binds MET804, PRO810, TRP812, ILE831, LYS833, LEU838, ASP841, TYR867 and 10 more

Residues it binds most

ILE 1, MET 1, ALA 1, ASP 1, CYS 1, GLU 1, LEU 1, LYS 1, PHE 1, PRO 1 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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