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Ligand · V6H

V6H · 2-[[2,5-bis(fluoranyl)phenyl]methylamino]-4-(cyclopentylamino)-N-[3-(2-oxidanylidenepyrrolidin-1-yl)propyl]pyrimidine-5-carboxamide

V6H, 2-[[2,5-bis(fluoranyl)phenyl]methylamino]-4-(cyclopentylamino)-N-[3-(2-oxidanylidenepyrrolidin-1-yl)propyl]pyrimidine-5-carboxamide (C24 H30 F2 N6 O2, 472.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component
V6H
Formula
C24 H30 F2 N6 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

V6H in 2 structures; the first of them:

  • 7OAM · Kinase domain of MERTK in complex with compound 8 · V6H B901 · binds LEU593, GLY594, VAL601, ALA617, LYS619, ILE650, LEU671, PRO672 and 10 more
  • 7OAM · Kinase domain of mertk in complex with compound 8 · V6H B901 · binds LEU593, GLY594, VAL601, ALA617, ILE650, LEU671, PRO672, PHE673 and 6 more

Residues it binds most

ALA 2, GLY 2, LEU 2, MET 2, LYS 2, ASP 2, ILE 2, PHE 2, PRO 2, TYR 1 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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