Ligand · V4Z

V4Z · 5-chloranyl-N2-[(1S)-1-(5-fluoranylpyridin-2-yl)ethyl]-N4-(3-propan-2-yloxy-1H-pyrazol-5-yl)pyrimidine-2,4-diamine

V4Z, 5-chloranyl-N2-[(1S)-1-(5-fluoranylpyridin-2-yl)ethyl]-N4-(3-propan-2-yloxy-1H-pyrazol-5-yl)pyrimidine-2,4-diamine (C17 H19 Cl F N7 O, 391.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component: V4Z
Formula: C17 H19 Cl F N7 O
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

V4Z in 2 structures; the first of them:

4AOJ · Human TrkA in complex with the inhibitor AZ-23 · V4Z A900 · binds LEU516, GLY517, GLU518, PHE521, VAL524, ALA542, LYS544, VAL573 and 15 more
4AOJ · Human trka in complex with the inhibitor az-23 · V4Z A900 · binds LEU516, GLY517, GLU518, PHE521, VAL524, ALA542, LYS544, VAL573 and 15 more

Residues it binds most

GLY 6, ARG 6, ASP 6, GLU 6, LEU 6, PHE 6, VAL 6, ALA 6, ASN 6, CYS 6 (residue and the binding sites it lines).

Found with

ZN · Zinc ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.