GL1X · GenesisL1 explorer

Ligand · UZK

UZK · (2S)-1-[[(1R,5S)-3-azabicyclo[3.1.0]hexan-3-yl]carbonyl]-N-(2-cyclopropylethyl)-2-methyl-4-oxidanylidene-3,5-dihydro-2H-1,5-benzodiazepine-7-carboxamide

UZK, (2S)-1-[[(1R,5S)-3-azabicyclo[3.1.0]hexan-3-yl]carbonyl]-N-(2-cyclopropylethyl)-2-methyl-4-oxidanylidene-3,5-dihydro-2H-1,5-benzodiazepine-7-carboxamide (C22 H28 N4 O3, 396.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2…

Component
UZK
Formula
C22 H28 N4 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

UZK in 2 structures; the first of them:

  • 7O2C · X-RAY STRUCTURE OF SMYD3 IN COMPLEX WITH the benzodiazepine-based probe BAY-6035 · UZK A501 · binds CYS180, SER182, PHE183, THR184, CYS186, MET190, ILE214, PHE216 and 5 more
  • 7O2C · X-ray structure of SMYD3 in complex with the benzodiazepine-based probe bay-6035 · UZK A501 · binds CYS180, SER182, PHE183, THR184, CYS186, MET190, ILE214, PHE216 and 5 more

Residues it binds most

CYS 2, PHE 2, TYR 2, HIS 2, ILE 2, MET 2, SAM 2, SER 2, THR 2, VAL 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

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