Ligand · UZE
UZE · 4-[4-[(4,4-dimethylpiperidin-1-yl)methyl]-2-fluoranyl-phenyl]-9-[6-(methylamino)pyrimidin-4-yl]-1,4,9-triazaspiro[5.5]undecan-2-one
UZE, 4-[4-[(4,4-dimethylpiperidin-1-yl)methyl]-2-fluoranyl-phenyl]-9-[6-(methylamino)pyrimidin-4-yl]-1,4,9-triazaspiro[5.5]undecan-2-one (C27 H38 F N7 O, 495.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…
- Component
- UZE
- Formula
- C27 H38 F N7 O
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
UZE in 2 structures; the first of them:
- 7O29 · Crystal structure of the human METTL3-METTL14 complex bound to Compound 20 (ADO_AD_044) · UZE A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, PRO396, PRO397, TYR406 and 12 more
- 7O29 · Crystal structure of the human METTL3-METTL14 complex bound to compound 20 (ADO_AD_044) · UZE A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, PRO396, PRO397, TYR406 and 9 more
Residues it binds most
ARG 2, ASP 2, PRO 2, GLY 2, TRP 2, ASN 2, CYS 2, GLU 2, ILE 2, LEU 2 (residue and the binding sites it lines).
Found with
- ACT · Acetate ion
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