GL1X · GenesisL1 explorer

Ligand · UZ2

UZ2 · 4-[4-[(4,4-dimethylpiperidin-1-yl)methyl]phenyl]-1-methyl-9-[6-(methylamino)pyrimidin-4-yl]-1,4,9-triazaspiro[5.5]undecan-2-one

UZ2, 4-[4-[(4,4-dimethylpiperidin-1-yl)methyl]phenyl]-1-methyl-9-[6-(methylamino)pyrimidin-4-yl]-1,4,9-triazaspiro[5.5]undecan-2-one (C28 H41 N7 O, 491.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component
UZ2
Formula
C28 H41 N7 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

UZ2 in 2 structures; the first of them:

  • 7O2H · Crystal structure of the human METTL3-METTL14 complex bound to Compound 13 (ADO_AD_091) · UZ2 A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, PRO396, PRO397, TYR406 and 12 more
  • 7O2H · Crystal structure of the human METTL3-METTL14 complex bound to compound 13 (ADO_AD_091) · UZ2 A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, PRO396, PRO397, TYR406 and 12 more

Residues it binds most

ASP 2, GLY 2, PRO 2, TRP 2, ARG 2, ASN 2, CYS 2, GLN 2, GLU 2, HIS 2 (residue and the binding sites it lines).

Found with

  • ACT · Acetate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.