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Ligand · UY5

UY5 · 4-[4-[(4,4-dimethylpiperidin-1-yl)methyl]phenyl]-9-[6-(propan-2-ylamino)pyrimidin-4-yl]-1,4,9-triazaspiro[5.5]undecan-2-one

UY5, 4-[4-[(4,4-dimethylpiperidin-1-yl)methyl]phenyl]-9-[6-(propan-2-ylamino)pyrimidin-4-yl]-1,4,9-triazaspiro[5.5]undecan-2-one (C29 H43 N7 O, 505.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
UY5
Formula
C29 H43 N7 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

UY5 in 2 structures; the first of them:

  • 7O0R · Crystal structure of the human METTL3-METTL14 complex bound to Compound 15 (ADO_AE_026) · UY5 A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, PRO396, PRO397, TYR406 and 13 more
  • 7O0R · Crystal structure of the human METTL3-METTL14 complex bound to compound 15 (ADO_AE_026) · UY5 A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, PRO396, PRO397, TYR406 and 13 more

Residues it binds most

GLY 2, ARG 2, ASP 2, PRO 2, ASN 2, CYS 2, GLN 2, GLU 2, ILE 2, LEU 2 (residue and the binding sites it lines).

Found with

  • ACT · Acetate ion

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