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Ligand · UXW

UXW · 4-[6-[(4,4-dimethylpiperidin-1-yl)methyl]pyridin-3-yl]-9-[6-[(phenylmethyl)amino]pyrimidin-4-yl]-1,4,9-triazaspiro[5.5]undecan-2-one

UXW, 4-[6-[(4,4-dimethylpiperidin-1-yl)methyl]pyridin-3-yl]-9-[6-[(phenylmethyl)amino]pyrimidin-4-yl]-1,4,9-triazaspiro[5.5]undecan-2-one (C32 H42 N8 O, 554.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component
UXW
Formula
C32 H42 N8 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

UXW in 2 structures; the first of them:

  • 7O0L · Crystal structure of the human METTL3-METTL14 complex bound to Compound 8 (ADO_AC_093) · UXW A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, PRO396, PRO397, TYR406 and 14 more
  • 7O0L · Crystal structure of the human METTL3-METTL14 complex bound to compound 8 (ADO_AC_093) · UXW A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, PRO396, PRO397, TYR406 and 12 more

Residues it binds most

GLY 2, ARG 2, ASP 2, PRO 2, TRP 2, ASN 2, CYS 2, GLN 2, GLU 2, ILE 2 (residue and the binding sites it lines).

Found with

  • ACT · Acetate ion

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