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Ligand · UWV

UWV · 2-fluoro-N-[(1H-pyrazol-3-yl)methyl]aniline

UWV, 2-fluoro-N-[(1H-pyrazol-3-yl)methyl]aniline (C10 H10 F N3, 191.2 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (3 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
UWV
Formula
C10 H10 F N3
Class
ligand
Structures
5
PDB entries
3

Binding sites

UWV in 5 structures; the first of them:

  • 5RKL · PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with Z1545196403 · UWV A1501 · binds PRO1340, PHE1341, VAL1345, TYR1350, TYR1353, SER1392, TYR1395, THR1396 and 4 more
  • 5RX7 · INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2… · UWV A901 · binds LEU614, SER615, LEU620, THR621, ARG623, ARG624
  • 5RKL · Pandda analysis group deposition -- crystal structure of phip in complex with Z1545196403 · UWV A1501 · binds PRO1340, PHE1341, VAL1345, TYR1350, SER1392, TYR1395, THR1396, PRO1397 and 3 more
  • 5RX7 · INPP5D pandda analysis group deposition -- crystal structure of the phosphatase and C2… · UWV A901 · binds LEU614, SER615, LEU620, THR621, ARG623, ARG624
  • 5RYU · EPB41L3 pandda analysis group deposition -- crystal structure of the ferm domain of human… · UWV A401 · binds CYS316, SER318, GLY319, LEU320, LEU321, ARG331, PHE332, ALA333

Residues it binds most

SER 5, TYR 2, LEU 3, ARG 3, PRO 2, THR 4, PHE 3, ILE 2, VAL 2, ALA 1 (residue and the binding sites it lines).

Found with

  • DMS · Dimethyl sulfoxide
  • EDO · 1,2-ethanediol

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