Ligand · UUI
UUI · (1S,5S,6R)-10-[[3,5-bis(chloranyl)phenyl]sulfonimidoyl]-5-ethenyl-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one
UUI, (1S,5S,6R)-10-[[3,5-bis(chloranyl)phenyl]sulfonimidoyl]-5-ethenyl-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one (C22 H24 Cl2 N4 O2 S, 479.4 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (3 PDB…
- Component
- UUI
- Formula
- C22 H24 Cl2 N4 O2 S
- Class
- ligand
- Structures
- 3
- PDB entries
- 3
Binding sites
UUI in 3 structures; the first of them:
- 8CHK · Human FKBP12 in complex with (1S,5S,6R)-10-((S)-(3,5-dichlorophenyl)sulfonimidoyl)-3-(pyri… · UUI A201 · binds TYR26, PHE36, ASP37, ARG42, PHE46, GLU54, VAL55, ILE56 and 6 more
- 8CHN · The FK1 domain of FKBP51 in complex with (1S,5S,6R)-10-((S)-(3,5-dichlorophenyl)sulfonimid… · UUI A201 · binds TYR47, PHE57, ASP58, ARG63, PHE67, GLN75, VAL76, ILE77 and 6 more
- 8CHR · The FK1 domain of FKBP51 in complex with (1S,5S,6R)-10-((R)-(3,5-dichlorophenyl)sulfonimid… · UUI A201 · binds TYR47, PHE57, ASP58, ARG63, PHE67, GLN75, VAL76, ILE77 and 6 more
Residues it binds most
PHE 5, ILE 5, TYR 5, ASP 5, TRP 5, VAL 5, ARG 3, GLU 3, HIS 3, LEU 3 (residue and the binding sites it lines).
Found with
- MES · 2-(N-morpholino)-ethanesulfonic acid
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