GL1X · GenesisL1 explorer

Ligand · UTF

UTF · (9~{S},12~{R},19~{S})-9-[[4-[[(2~{S})-2-cyclohexyl-2-(2-phenylethanoylamino)ethanoyl]amino]phenyl]methyl]-12-methyl-7,10,13,21-tetrakis(oxidanylidene)-8,11,14,20-tetrazaspiro[4.17]docosane-19-carboxylic acid

UTF, (9~{S},12~{R},19~{S})-9-[[4-[[(2~{S})-2-cyclohexyl-2-(2-phenylethanoylamino)ethanoyl]amino]phenyl]methyl]-12-methyl-7,10,13,21-tetrakis(oxidanylidene)-8,11,14,20-tetrazaspiro[4.17]docosane-19-carboxylic acid (C43 H58 N6 O8, 787.0…

Component
UTF
Formula
C43 H58 N6 O8
Class
ligand
Structures
1
PDB entries
1

Binding sites

UTF in 1 structure; the first of them:

  • 8CDG · Crystal structure of human IL-17A cytokine in complex with macrocycle · UTF A201 · binds TYR62, PRO63, VAL65, ILE66, TRP67, GLN94, GLU95, ILE96 and 10 more

Residues it binds most

LEU 1, ILE 1, GLU 1, PRO 1, VAL 1, GLN 1, LYS 1, TRP 1, TYR 1 (residue and the binding sites it lines).

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