UPT · 1-[(2R,3aR,4R,6R,6aR)-2-hydroxy-6-(hydroxymethyl)-2-sulfidotetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-4-yl]pyrimidine-2,4(1H,3H)-dione

Binding sites

UPT in 2 structures; the first of them:

• 4R09 · Crystal structure of human TLR8 in complex with ORN06S · UPT A903 · binds PRO264, PHE265, PHE320, PHE346, ARG375, ILE403, PHE467, TYR468 and 5 more
• 4R09 · Crystal structure of human TLR8 in complex with ORN06S · UPT A903 · binds PRO264, PHE265, PHE320, PHE346, ARG375, ILE403, PHE467, TYR468 and 5 more

Residues it binds most

PHE 8, ILE 8, ALA 8, ARG 8, GLY 8, HIS 8, PRO 8, TYR 8, ASN 2 (residue and the binding sites it lines).

Found with

• 06S · O-[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-2-({[(S)-({(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-2-[(thiophosphonooxy)methyl]tetrahydrofuran-3-yl}oxy)(sulfanyl)phosphoryl]oxy}methyl)-4-hydroxytetrahydrofuran-3-yl] dihydrogen (S)-phosphorothioate
• URI · Uridine
• BMA · beta-D-mannopyranose
• MAN · alpha-D-mannopyranose
• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose