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Ligand · UO5

UO5 · 6-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-2-[2-oxidanylidene-2-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]-3~{H}-isoindol-1-one

UO5, 6-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-2-[2-oxidanylidene-2-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]-3~{H}-isoindol-1-one (C29 H30 Cl N5 O3, 532.0 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component
UO5
Formula
C29 H30 Cl N5 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

UO5 in 2 structures; the first of them:

  • 7NR3 · Discovery of ASTX029, a clinical candidate which modulates the phosphorylation and… · UO5 A403 · binds ILE31, GLU33, GLY34, TYR36, GLY37, MET38, VAL39, ALA52 and 15 more
  • 7NR3 · Discovery of ASTX029, a clinical candidate which modulates the phosphorylation and… · UO5 A403 · binds ILE31, GLU33, GLY34, TYR36, GLY37, MET38, VAL39, ALA52 and 15 more

Residues it binds most

ASP 2, GLU 2, ILE 2, GLY 2, LEU 2, LYS 2, MET 2, ALA 2, CYS 2, GLN 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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