UM4 · 4-{8-amino-3-[(6R,8aS)-3-oxooctahydroindolizin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-3-(cyclopropyloxy)-N-[4-(trifluoromethyl)pyridin-2-yl]benzamide

Binding sites

UM4 in 2 structures; the first of them:

• 6X3P · Co-structure of BTK kinase domain with L-005298385 inhibitor · UM4 A701 · binds LEU408, GLY409, THR410, GLY411, VAL416, ALA428, LYS430, PHE442 and 21 more
• 6X3P · Co-structure of btk kinase domain with L-005298385 inhibitor · UM4 A701 · binds LEU408, GLY409, THR410, GLY411, VAL416, ALA428, LYS430, PHE442 and 21 more

Residues it binds most

LEU 4, MET 4, ASN 4, GLY 2, TYR 4, VAL 4, ALA 2, ASP 4, CYS 2, ILE 4 (residue and the binding sites it lines).

Found with

• BTB · 2-[bis-(2-hydroxy-ethyl)-amino]-2-hydroxymethyl-propane-1,3-diol
• EDO · 1,2-ethanediol