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Ligand · UEZ

UEZ · (R)-1-(6-(benzylamino)pyrimidin-4-yl)-3-(((6-((4,4-dimethylpiperidin-1-yl)methyl)naphthalen-1-yl)amino) methyl)piperidin-3-ol

UEZ, (R)-1-(6-(benzylamino)pyrimidin-4-yl)-3-(((6-((4,4-dimethylpiperidin-1-yl)methyl)naphthalen-1-yl)amino) methyl)piperidin-3-ol (C35 H44 N6 O, 564.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
UEZ
Formula
C35 H44 N6 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

UEZ in 2 structures; the first of them:

  • 7NID · Crystal structure of the human METTL3-METTL14 complex with compound UOZ078 · UEZ A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, PRO396, PRO397, TYR406 and 15 more
  • 7NID · Crystal structure of the human METTL3-METTL14 complex with compound UOZ078 · UEZ A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, GLY407, THR408, LEU409 and 11 more

Residues it binds most

GLY 2, ARG 2, ASP 2, TRP 2, ASN 2, CYS 2, GLN 2, GLU 2, HIS 2, ILE 2 (residue and the binding sites it lines).

Found with

  • ACT · Acetate ion

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