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Ligand · UEW

UEW · N-(((R)-1-(6-(benzylamino)pyrimidin-4-yl)-3-hydroxypiperidin-3-yl)methyl)-4-(((S)-1-isopropyl-2-azaspiro[3.3]heptan-2-yl)methyl)benzamide

UEW, N-(((R)-1-(6-(benzylamino)pyrimidin-4-yl)-3-hydroxypiperidin-3-yl)methyl)-4-(((S)-1-isopropyl-2-azaspiro[3.3]heptan-2-yl)methyl)benzamide (C34 H44 N6 O2, 568.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component
UEW
Formula
C34 H44 N6 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

UEW in 2 structures; the first of them:

  • 7NI9 · Crystal structure of the human METTL3-METTL14 complex with compound UOZ058 · UEW A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, PRO396, PRO397, TRP398 and 17 more
  • 7NI9 · Crystal structure of the human METTL3-METTL14 complex with compound UOZ058 · UEW A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, PRO396, TRP398, GLY407 and 14 more

Residues it binds most

TRP 2, GLY 2, ARG 2, ASP 2, THR 2, PRO 2, ASN 2, CYS 2, GLN 2, GLU 2 (residue and the binding sites it lines).

Found with

  • ACT · Acetate ion

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