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Ligand · UE2

UE2 · (R)-N-((3-hydroxy-1-(6-(methylamino)pyrimidin-4-yl) piperidin-3-yl)methyl)-4-((4-methylpiperidin-1-yl) methyl)benzamide

UE2, (R)-N-((3-hydroxy-1-(6-(methylamino)pyrimidin-4-yl) piperidin-3-yl)methyl)-4-((4-methylpiperidin-1-yl) methyl)benzamide (C26 H38 N6 O2, 466.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
UE2
Formula
C26 H38 N6 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

UE2 in 2 structures; the first of them:

  • 7NHI · Crystal structure of the human METTL3-METTL14 complex with compound UOZ004 · UE2 A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, PRO396, PRO397, TYR406 and 14 more
  • 7NHI · Crystal structure of the human METTL3-METTL14 complex with compound UOZ004 · UE2 A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, TYR406, GLY407, LEU409 and 9 more

Residues it binds most

GLY 2, ARG 2, ASP 2, TRP 2, ASN 2, CYS 2, GLN 2, GLU 2, ILE 2, LEU 2 (residue and the binding sites it lines).

Found with

  • ACT · Acetate ion

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