GL1X · GenesisL1 explorer

Ligand · UDG

UDG · (2R,3R,4R,5S,6R)-2-{[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)-3-{[(3R)-3-hydroxytetradecanoyl]amino}tetrahydro-2H-pyran-4-yl (3R)-3-hydroxytetradecanoate

UDG, (2R,3R,4R,5S,6R)-2-{[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)-3-{[(3R)-3-hydroxytetrade…

Component
UDG
Formula
C43 H77 N3 O20 P2
Class
ligand
Structures
2
PDB entries
1

Binding sites

UDG in 2 structures; the first of them:

  • 4J6E · Structure of LPXI D225A Mutant · UDG A301 · binds GLY10, GLY11, ALA12, LEU13, LEU33, VAL49, ILE51, GLU53 and 36 more
  • 4J6E · Structure of lpxi D225A mutant · UDG A301 · binds GLY10, GLY11, ALA12, LEU13, LEU33, VAL49, ILE51, GLU53 and 36 more

Residues it binds most

LEU 2, VAL 2, GLY 2, ALA 2, PHE 2, ILE 2, THR 2, ASP 2, GLU 2, PRO 2 (residue and the binding sites it lines).

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