UCG · 3'-O-[(R)-{[(2R,3aR,4R,6R,6aR)-6-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-hydroxy-2-oxidotetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-4-yl]methoxy}(hydroxy)phosphoryl]uridine 5'-(dihydrogen phosphate)

Binding sites

UCG in 4 structures; the first of them:

• 4R07 · Crystal structure of human TLR8 in complex with ORN06 · UCG A902 · binds TYR291, LYS314, VAL315, GLU340, ILE341, ASP343, SER345, ARG370 and 10 more
• 4R08 · Crystal structure of human TLR8 in complex with ssRNA40 · UCG A915 · binds TYR291, LYS314, VAL315, GLU340, ILE341, ASP343, SER345, ARG370 and 10 more
• 4R07 · Crystal structure of human TLR8 in complex with ORN06 · UCG A902 · binds TYR291, LYS314, VAL315, GLU340, ILE341, ASP343, SER345, ARG370 and 10 more
• 4R08 · Crystal structure of human TLR8 in complex with SSRNA40 · UCG A915 · binds TYR291, LYS314, VAL315, GLU340, ILE341, ASP343, SER345, ARG370 and 10 more

Residues it binds most

ARG 16, HIS 16, ASN 16, GLU 16, ASP 16, THR 16, ILE 16, LEU 16, LYS 16, PHE 16 (residue and the binding sites it lines).

Found with

• URI · Uridine
• BMA · beta-D-mannopyranose
• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
• MAN · alpha-D-mannopyranose