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Ligand · UB0

UB0 · (5P)-3-(carboxymethoxy)-4-chloro-5-(3-{[(4S)-1-({3-[2-(4-{3-[(3R)-2,6-dioxopiperidin-3-yl]-2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl}piperidin-1-yl)acetamido]phenyl}methanesulfonyl)-2,2-dimethylpiperidin-4-yl]amino}phenyl)thiophene-2-carboxylic acid

UB0, (5P)-3-(carboxymethoxy)-4-chloro-5-(3-{[(4S)-1-({3-[2-(4-{3-[(3R)-2,6-dioxopiperidin-3-yl]-2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl}piperidin-1-yl)acetamido]phenyl}methanesulfonyl)-2,2-dimethylpiperidin-4-yl]amino}phenyl)thiophene-2-carbo…

Component
UB0
Formula
C46 H49 Cl N6 O12 S2
Class
ligand
Structures
1
PDB entries
1

Binding sites

UB0 in 1 structure; the first of them:

  • 8U0H · Crystal structure of PTPN2 with a PROTAC · UB0 A801 · binds ARG26, ASN27, SER29, HIS30, ASP31, TYR48, ASP50, VAL51 and 20 more

Residues it binds most

ARG 2, ASP 2, GLY 2, TYR 2, GLN 2, PHE 2, SER 2, ALA 2, ASN 2, CYS 2 (residue and the binding sites it lines).

Found with

  • NA · Sodium ion
  • ACT · Acetate ion

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