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Ligand · UAG

UAG · Uridine-5'-diphosphate-N-acetylmuramoyl-L-alanine-D-glutamate

UAG, Uridine-5'-diphosphate-N-acetylmuramoyl-L-alanine-D-glutamate (C28 H43 N5 O23 P2, 879.6 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues…

Component
UAG
Formula
C28 H43 N5 O23 P2
Class
ligand
Structures
8
PDB entries
4

Binding sites

UAG in 8 structures; the first of them:

  • 1E8C · Structure of MurE the UDP-N-acetylmuramyl tripeptide synthetase from E. coli · UAG A1498 · binds LEU26, ASP27, SER28, ARG29, PHE37, VAL40, GLY42, HIS43 and 15 more
  • 2WTZ · MurE ligase of Mycobacterium Tuberculosis · UAG A1498 · binds LEU67, ARG68, ALA69, GLN70, PHE78, LEU81, THR82, GLY83 and 17 more
  • 2XJA · Structure of MurE from M.tuberculosis with dipeptide and ADP · UAG A1536 · binds LEU67, ARG68, ALA69, GLN70, PHE78, LEU81, THR82, GLY83 and 20 more
  • 4UAG · Udp-N-acetylmuramoyl-L-ALANINE:D-glutamate ligase · UAG A460 · binds ILE11, GLY12, GLY14, LEU15, THR16, GLY17, ASP35, THR36 and 23 more
  • 1E8C · Structure of mure the udp-N-acetylmuramyl tripeptide synthetase from E. COLI · UAG A1498 · binds LEU26, ASP27, SER28, ARG29, PHE37, VAL40, GLY42, HIS43 and 15 more
  • 2WTZ · Mure ligase of mycobacterium tuberculosis · UAG A1498 · binds LEU67, ARG68, ALA69, GLN70, PHE78, LEU81, THR82, GLY83 and 17 more
  • 2XJA · Structure of mure from M.TUBERCULOSIS with dipeptide and ADP · UAG A1536 · binds LEU67, ARG68, ALA69, GLN70, PHE78, LEU81, THR82, GLY83 and 20 more
  • 4UAG · Udp-N-acetylmuramoyl-L-ALANINE:D-glutamate ligase · UAG A460 · binds ILE11, GLY12, GLY14, LEU15, THR16, GLY17, ASP35, THR36 and 23 more

Residues it binds most

THR 22, HIS 22, LEU 22, ARG 22, GLY 22, SER 22, GLN 22, PHE 22, ALA 22, GLU 16 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ADP · Adenosine-5'-diphosphate
  • API · 2,6-diaminopimelic acid
  • CL · Chloride ion
  • SO4 · Sulfate ion
  • UNX · Unknown atom or ion

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