Ligand · UA4

UA4 · (2S)-6-(2,4-diamino-6-ethylpyrimidin-5-yl)-2-(3,5-difluorophenyl)-4-(3-methoxypropyl)-2-methyl-2H-1,4-benzoxazin-3(4H)-one

UA4, (2S)-6-(2,4-diamino-6-ethylpyrimidin-5-yl)-2-(3,5-difluorophenyl)-4-(3-methoxypropyl)-2-methyl-2H-1,4-benzoxazin-3(4H)-one (C25 H27 F2 N5 O3, 483.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component: UA4
Formula: C25 H27 F2 N5 O3
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

UA4 in 2 structures; the first of them:

2I4Q · Human renin/PF02342674 complex · UA4 A336 · binds THR13, GLN14, TYR15, VAL31, ASP33, GLY35, SER36, TYR78 and 14 more
2I4Q · Human RENIN/PF02342674 complex · UA4 A336 · binds THR13, GLN14, TYR15, VAL31, ASP33, GLY35, SER36, TYR78 and 14 more

Residues it binds most

SER 4, THR 4, TYR 4, ALA 4, ASP 4, GLY 4, PHE 4, VAL 4, GLN 4, LEU 4 (residue and the binding sites it lines).

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