GL1X · GenesisL1 explorer

Ligand · U9E

U9E · 3-(2-chlorophenyl)-4-ethyl-5-(1~{H}-indol-4-yl)-1~{H}-pyrrole-2-carboxylic acid

U9E, 3-(2-chlorophenyl)-4-ethyl-5-(1~{H}-indol-4-yl)-1~{H}-pyrrole-2-carboxylic acid (C21 H17 Cl N2 O2, 364.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5…

Component
U9E
Formula
C21 H17 Cl N2 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

U9E in 2 structures; the first of them:

  • 7ND1 · First-in-class small molecule inhibitors of Polycomb Repressive Complex 1 (PRC1) RING… · U9E A203 · binds MET62, ILE76, ILE77, LEU80, LYS85, LEU94, VAL95, SER96 and 2 more
  • 7ND1 · First-in-class small molecule inhibitors of polycomb repressive complex 1 (PRC1) ring… · U9E A203 · binds MET62, ILE76, ILE77, LEU80, LEU94, SER96, LYS97, LEU100

Residues it binds most

LEU 2, ILE 2, LYS 2, MET 2, SER 2, VAL 1 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.