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Ligand · U7K

U7K · (E)-3-((5,6-dihydro-2H,4H-thiazolo[5,4,3-ij]quinolin-2-ylidene)amino)-2-hydroxy-1-(4-(isoquinolin-5-yl) piperazin-1-yl)-2-methylpropan-1-one

U7K, (E)-3-((5,6-dihydro-2H,4H-thiazolo[5,4,3-ij]quinolin-2-ylidene)amino)-2-hydroxy-1-(4-(isoquinolin-5-yl) piperazin-1-yl)-2-methylpropan-1-one (C27 H29 N5 O2 S, 487.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1…

Component
U7K
Formula
C27 H29 N5 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

U7K in 2 structures; the first of them:

  • 7NBM · Co-crystal structure of Human Nicotinamide N-methyltransferase (NNMT) with the… · U7K A301 · binds LYS8, TYR11, PHE15, TYR20, TYR24, GLY63, GLY65, PRO66 and 18 more
  • 7NBM · Co-crystal structure of human nicotinamide N-methyltransferase (nnmt) with the… · U7K A301 · binds LYS8, TYR11, PHE15, TYR20, GLY65, ASP85, TYR86, ASN90 and 12 more

Residues it binds most

TYR 8, ALA 8, ASP 8, SER 8, CYS 8, GLY 8, ASN 8, LEU 8, LYS 8, PHE 8 (residue and the binding sites it lines).

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