Ligand · U6N

U6N · (2~{R})-2-[[7-but-2-ynyl-5-(3-chloranyl-2-methyl-phenyl)-6-ethyl-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-3-phenyl-propanoic acid

U6N, (2~{R})-2-[[7-but-2-ynyl-5-(3-chloranyl-2-methyl-phenyl)-6-ethyl-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-3-phenyl-propanoic acid (C28 H27 Cl N4 O2, 487.0 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component: U6N
Formula: C28 H27 Cl N4 O2
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

U6N in 2 structures; the first of them:

7NB7 · Structure of Mcl-1 complex with compound 6b · U6N A401 · binds HIS224, ALA227, PHE228, MET231, VAL249, MET250, VAL253, PHE254 and 8 more
7NB7 · Structure of mcl-1 complex with compound 6B · U6N A401 · binds HIS224, ALA227, PHE228, MET231, VAL249, MET250, VAL253, PHE254 and 8 more

Residues it binds most

PHE 8, VAL 8, ALA 8, HIS 8, MET 8, ARG 8, GLY 8, LEU 8, THR 8, ILE 6 (residue and the binding sites it lines).

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