GL1X · GenesisL1 explorer

Ligand · U6K

U6K · (2~{R},3~{R},4~{S},5~{R})-2-[(4~{a}~{S},7~{a}~{S})-4-azanyl-1,4,4~{a},7~{a}-tetrahydropyrrolo[2,3-d]pyrimidin-7-yl]-5-(quinolin-7-yloxymethyl)oxolane-3,4-diol

U6K, (2~{R},3~{R},4~{S},5~{R})-2-[(4~{a}~{S},7~{a}~{S})-4-azanyl-1,4,4~{a},7~{a}-tetrahydropyrrolo[2,3-d]pyrimidin-7-yl]-5-(quinolin-7-yloxymethyl)oxolane-3,4-diol (C20 H23 N5 O4, 397.4 g/mol), in the MolNFT structures on GenesisL1: bound…

Component
U6K
Formula
C20 H23 N5 O4
Class
ligand
Structures
1
PDB entries
1

Binding sites

U6K in 1 structure; the first of them:

  • 7BO7 · CRYSTAL STRUCTURE OF THE HUMAN PRMT5:MEP50 COMPLEX with JNJB44355437 · U6K AAA701 · binds PRO314, LEU315, TYR324, PHE327, LYS333, TYR334, GLY365, GLY367 and 15 more

Residues it binds most

GLU 1, LEU 1, GLY 1, LYS 1, SER 1, TYR 1, ARG 1, ASN 1, ASP 1, CYS 1 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol
  • EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid
  • PEG · Di(hydroxyethyl)ether

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