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Ligand · U3Z

U3Z · (3~{R})-3-(4-chlorophenyl)-2-[(4-ethynylphenyl)methyl]-3-[[1-(hydroxymethyl)cyclopropyl]methoxy]-6-(2-oxidanylpropan-2-yl)isoindol-1-one

U3Z, (3~{R})-3-(4-chlorophenyl)-2-[(4-ethynylphenyl)methyl]-3-[[1-(hydroxymethyl)cyclopropyl]methoxy]-6-(2-oxidanylpropan-2-yl)isoindol-1-one (C31 H30 Cl N O4, 516.0 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component
U3Z
Formula
C31 H30 Cl N O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

U3Z in 2 structures; the first of them:

  • 7BMG · Inhibitor of MDM2-p53 Interaction · U3Z A204 · binds LEU54, PHE55, LEU57, GLY58, GLN59, ILE61, MET62, TYR67 and 10 more
  • 7BMG · Inhibitor of MDM2-P53 interaction · U3Z A204 · binds LEU54, PHE55, LEU57, GLY58, GLN59, ILE61, MET62, TYR67 and 10 more

Residues it binds most

ILE 2, PHE 2, GLN 2, HIS 2, LEU 2, TYR 2, VAL 2, GLY 2, MET 2 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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