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Ligand · TZN

TZN · [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl][(2R)-tetrahydrofuran-2-yl]methanone

TZN, [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl][(2R)-tetrahydrofuran-2-yl]methanone (C19 H25 N5 O4, 387.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues…

Component
TZN
Formula
C19 H25 N5 O4
Class
ligand
Structures
4
PDB entries
2

Binding sites

TZN in 4 structures; the first of them:

  • 4O33 · Crystal Structure of human PGK1 3PG and terazosin(TZN) ternary complex · TZN A501 · binds GLY213, ALA214, GLY237, GLY238, PHE241, THR254, SER255, LEU256 and 9 more
  • 4O3F · Crystal Structure of mouse PGK1 3PG and terazosin(TZN) ternary complex · TZN A501 · binds GLY214, ALA215, GLY238, GLY239, PHE242, THR255, SER256, LEU257 and 9 more
  • 4O33 · Crystal structure of human PGK1 3PG and TERAZOSIN(TZN) ternary complex · TZN A501 · binds GLY213, ALA214, GLY237, GLY238, PHE241, THR254, SER255, LEU256 and 9 more
  • 4O3F · Crystal structure of mouse PGK1 3PG and TERAZOSIN(TZN) ternary complex · TZN A501 · binds GLY214, ALA215, GLY238, GLY239, PHE242, THR255, SER256, LEU257 and 9 more

Residues it binds most

GLY 4, LEU 4, PHE 4, VAL 4, ALA 4, ASP 4, MET 4, PRO 4, SER 4, THR 4 (residue and the binding sites it lines).

Found with

  • 3PG · 3-phosphoglyceric acid

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