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Ligand · TZG

TZG · (S)-2-amino-3-(2-(2-carboxyethyl)-5-chloro-4-nitrophenyl)propionic acid

TZG, (S)-2-amino-3-(2-(2-carboxyethyl)-5-chloro-4-nitrophenyl)propionic acid (C12 H13 Cl N2 O6, 316.7 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the…

Component
TZG
Formula
C12 H13 Cl N2 O6
Class
ligand
Structures
4
PDB entries
2

Binding sites

TZG in 4 structures; the first of them:

  • 3TZA · Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the… · TZG A261 · binds GLU10, TYR13, TYR58, PRO86, LEU87, THR88, ARG93, LEU135 and 9 more
  • 4DLD · Crystal structure of the GluK1 ligand-binding domain (S1S2) in complex with the… · TZG A301 · binds GLU13, TYR16, TYR61, PRO88, LEU89, THR90, ARG95, VAL137 and 8 more
  • 3TZA · Crystal structure of the GLUA2 ligand-binding domain (S1S2J) in complex with the… · TZG A261 · binds GLU10, TYR13, TYR58, PRO86, LEU87, THR88, ARG93, LEU135 and 9 more
  • 4DLD · Crystal structure of the GLUK1 ligand-binding domain (S1S2) in complex with the… · TZG A301 · binds GLU13, TYR16, TYR61, PRO88, LEU89, THR90, ARG95, VAL137 and 8 more

Residues it binds most

TYR 8, THR 8, GLU 8, LEU 8, SER 8, MET 8, ARG 8, PRO 8, GLY 4, VAL 4 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • CL · Chloride ion
  • GOL · Glycerol

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