GL1X · GenesisL1 explorer

Ligand · TZ5

TZ5 · 3,8-diamino-6-phenyl-5-[6-[1-[2-[(1,2,3,4-tetrahydro-9-acridinyl)amino]ethyl]-1H-1,2,3-triazol-5-yl]hexyl]-phenanthridinium

TZ5, 3,8-diamino-6-phenyl-5-[6-[1-[2-[(1,2,3,4-tetrahydro-9-acridinyl)amino]ethyl]-1H-1,2,3-triazol-5-yl]hexyl]-phenanthridinium (C42 H45 N8 +1, 661.9 g/mol), in the MolNFT structures on GenesisL1: bound in 10 records (5 PDB entries).…

Component
TZ5
Formula
C42 H45 N8 +1
Class
ligand
Structures
10
PDB entries
5

Binding sites

TZ5 in 10 structures; the first of them:

  • 1Q83 · Crystal structure of the mouse acetylcholinesterase-TZ2PA6 syn complex · TZ5 A1951 · binds TYR72, LEU76, GLY82, TRP86, GLY120, GLY121, GLY122, TYR124 and 14 more
  • 2XUI · Crystal structure of mache-Y337A-TZ2PA6 syn complex (1 wk) · TZ5 A1545 · binds TYR72, VAL73, ASP74, LEU76, GLY82, TRP86, GLY120, GLY121 and 21 more
  • 2XUJ · Crystal structure of mache-Y337A-TZ2PA6 syn complex (1 mth) · TZ5 A1544 · binds TYR72, LEU76, GLY82, TRP86, GLY120, GLY121, GLY122, TYR124 and 16 more
  • 2XUK · Crystal structure of mache-Y337A-TZ2PA6 syn complex (10 mth) · TZ5 A1543 · binds TYR72, ASP74, LEU76, GLY82, TRP86, GLY120, GLY121, GLY122 and 17 more
  • 2XUP · CRYSTAL STRUCTURE OF the MACHE-Y337A mutant in complex with soaked TZ2PA6 SYN inhibitor · TZ5 A1548 · binds TYR72, VAL73, ASP74, LEU76, GLY82, TRP86, GLY120, GLY121 and 21 more
  • 1Q83 · Crystal structure of the mouse acetylcholinesterase-TZ2PA6 syn complex · TZ5 A1951 · binds TYR72, LEU76, GLY82, TRP86, GLY120, GLY121, GLY122, TYR124 and 14 more
  • 2XUI · Crystal structure of mache-Y337A-TZ2PA6 syn complex (1 wk) · TZ5 A1545 · binds TYR72, VAL73, ASP74, LEU76, GLY82, TRP86, GLY120, GLY121 and 21 more
  • 2XUJ · Crystal structure of mache-Y337A-TZ2PA6 syn complex (1 mth) · TZ5 A1544 · binds TYR72, LEU76, GLY82, TRP86, GLY120, GLY121, GLY122, TYR124 and 16 more
  • 2XUK · Crystal structure of mache-Y337A-TZ2PA6 syn complex (10 mth) · TZ5 A1543 · binds TYR72, ASP74, LEU76, GLY82, TRP86, GLY120, GLY121, GLY122 and 17 more
  • 2XUP · Crystal structure of the mache-Y337A mutant in complex with soaked TZ2PA6 syn inhibitor · TZ5 A1548 · binds TYR72, VAL73, ASP74, LEU76, GLY82, TRP86, GLY120, GLY121 and 21 more

Residues it binds most

GLY 20, TYR 20, TRP 20, SER 20, PHE 20, GLU 20, LEU 20, HIS 20, ALA 16, ASP 16 (residue and the binding sites it lines).

Found with

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • P6G · Hexaethylene glycol
  • FUC · alpha-L-fucopyranose
  • FUL · beta-L-fucopyranose
  • SO3 · Sulfite ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.