Ligand · TVH

TVH · (3~{R})-4-chloranyl-3-(4-chlorophenyl)-3-[[1-(hydroxymethyl)cyclopropyl]methoxy]-2-[(4-nitrophenyl)methyl]isoindol-1-one

TVH, (3~{R})-4-chloranyl-3-(4-chlorophenyl)-3-[[1-(hydroxymethyl)cyclopropyl]methoxy]-2-[(4-nitrophenyl)methyl]isoindol-1-one (C26 H22 Cl2 N2 O5, 513.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component: TVH
Formula: C26 H22 Cl2 N2 O5
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

TVH in 2 structures; the first of them:

7BJ0 · Inhibitor of MDM2-p53 Interaction · TVH A201 · binds ILE19, LEU54, PHE55, LEU57, GLY58, GLN59, ILE61, MET62 and 7 more
7BJ0 · Inhibitor of MDM2-P53 interaction · TVH A201 · binds LEU54, PHE55, LEU57, GLY58, GLN59, ILE61, MET62, TYR67 and 5 more

Residues it binds most

ILE 4, PHE 4, LEU 4, TYR 4, GLN 4, GLY 4, HIS 4, MET 4, VAL 4, SER 2 (residue and the binding sites it lines).

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