Ligand · TV5

TV5 · (3~{R})-2-[(5-chloranylpyridin-2-yl)methyl]-3-(4-chlorophenyl)-4-fluoranyl-3-[(1-oxidanylcyclopropyl) methoxy]-6-(2-oxidanylpropan-2-yl)isoindol-1-one

TV5, (3~{R})-2-[(5-chloranylpyridin-2-yl)methyl]-3-(4-chlorophenyl)-4-fluoranyl-3-[(1-oxidanylcyclopropyl) methoxy]-6-(2-oxidanylpropan-2-yl)isoindol-1-one (C27 H25 Cl2 F N2 O4, 531.4 g/mol), in the MolNFT structures on GenesisL1: bound in…

Component: TV5
Formula: C27 H25 Cl2 F N2 O4
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

TV5 in 2 structures; the first of them:

7BIT · Inhibitor of MDM2-p53 Interaction · TV5 A202 · binds LEU54, PHE55, LEU57, GLY58, GLN59, ILE61, MET62, TYR67 and 11 more
7BIT · Inhibitor of MDM2-P53 interaction · TV5 A202 · binds LEU54, LEU57, GLY58, ILE61, MET62, TYR67, GLN72, HIS73 and 6 more

Residues it binds most

ILE 2, HIS 2, LEU 2, PHE 2, TYR 2, GLN 2, VAL 2, GLY 2, MET 2 (residue and the binding sites it lines).

Found with

SO4 · Sulfate ion

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