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Ligand · TUY

TUY · (3S,5S,9R,20R,21R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9,20, 21-pentahydroxy-8,8-dimethyl-10,14,19-trioxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphadocosan-22-oic acid 3,5-dioxide (non-preferred name)

TUY, (3S,5S,9R,20R,21R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9,20, 21-pentahydroxy-8,8-dimethyl-10,14,19-trioxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphadocosan-22-oic acid…

Component
TUY
Formula
C25 H40 N7 O21 P3 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

TUY in 2 structures; the first of them:

  • 6WCV · Tartryl-CoA bound to human GTP-specific succinyl-CoA synthetase · TUY A401 · binds GLN21, GLY22, THR24, GLY25, LYS26, GLN27, GLY28, THR46 and 24 more
  • 6WCV · Tartryl-CoA bound to human GTP-specific succinyl-CoA synthetase · TUY A401 · binds GLY22, THR24, GLY25, LYS26, GLN27, THR46, THR47, PRO48 and 21 more

Residues it binds most

GLY 2, THR 2, PRO 2, ILE 2, LYS 2, ALA 2, GLN 2, ASN 2, CYS 2, GLU 2 (residue and the binding sites it lines).

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