Ligand · TT8
TT8 · (2S)-2-azanyl-4-[[(2S,3S,4R,5R)-5-[6-(methylamino)purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl]butanoic acid
TT8, (2S)-2-azanyl-4-[[(2S,3S,4R,5R)-5-[6-(methylamino)purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl]butanoic acid (C15 H22 N6 O5 S, 398.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…
- Component
- TT8
- Formula
- C15 H22 N6 O5 S
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
TT8 in 2 structures; the first of them:
- 3SR4 · Crystal Structure of Human DOT1L in Complex with a Selective Inhibitor · TT8 A417 · binds PRO133, GLU134, VAL135, TYR136, GLY137, GLU138, THR139, ASP161 and 17 more
- 3SR4 · Crystal structure of human DOT1L in complex with a selective inhibitor · TT8 A417 · binds PRO133, GLU134, VAL135, TYR136, GLY137, GLU138, THR139, ASP161 and 17 more
Residues it binds most
GLY 2, GLU 2, PHE 2, VAL 2, ASP 2, PRO 2, ALA 2, ASN 2, GLN 2, LEU 2 (residue and the binding sites it lines).
Found with
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