GL1X · GenesisL1 explorer

Ligand · TSC

TSC · (1S)-1-amino-2-(1H-indol-3-yl)ethanol

TSC, (1S)-1-amino-2-(1H-indol-3-yl)ethanol (C10 H12 N2 O, 176.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
TSC
Formula
C10 H12 N2 O
Class
ligand
Structures
4
PDB entries
2

Binding sites

TSC in 4 structures; the first of them:

  • 2AGZ · Crystal structure of the carbinolamine intermediate in the reductive half-reaction of… · TSC D190 · binds ASP84, TRQ109, ASP128, ASN156, ASP157, VAL158, ASN159, TRP160 and 9 more
  • 2AH0 · Crystal structure of the carbinolamine intermediate in the reductive half-reaction of… · TSC H1 · binds ASP84, TRQ109, ASP128, ASN156, ASP157, VAL158, ASN159, TRP160 and 9 more
  • 2AGZ · Crystal structure of the carbinolamine intermediate in the reductive half-reaction of… · TSC D190 · binds ASP84, TRQ109, ASP128, ASN156, ASP157, VAL158, ASN159, TRP160 and 9 more
  • 2AH0 · Crystal structure of the carbinolamine intermediate in the reductive half-reaction of… · TSC H1 · binds ASP84, TRQ109, ASP128, ASN156, ASP157, VAL158, ASN159, TRP160 and 9 more

Residues it binds most

ASN 6, ASP 6, PHE 6, LEU 6, GLY 6, GLN 6, THR 6, TRP 6, TRQ 6, VAL 6 (residue and the binding sites it lines).

Found with

  • TSH · 2-(1H-indol-3-yl)ethanimine
  • ZN · Zinc ion

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