TPV · N-(3-{(1R)-1-[(6R)-4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl]propyl}phenyl)-5-(trifluoromethyl)-2-pyridinesulfonamide

Binding sites

TPV in 3 structures; the first of them:

• 6DIF · Wild-type HIV-1 protease in complex with tipranavir · TPV B201 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32 and 20 more
• 6DIF · Wild-type HIV-1 protease in complex with tipranavir · TPV B201 · binds ARG8, LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, ILE47 and 15 more
• 6DIL · HIV-1 protease with single mutation L76V in complex with tipranavir · TPV B201 · binds LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32, ILE47 and 16 more

Residues it binds most

GLY 3, ILE 3, ASP 3, VAL 3, LEU 3, ALA 3, ARG 3, PRO 3 (residue and the binding sites it lines).

Found with

• NA · Sodium ion
• CL · Chloride ion
• GOL · Glycerol
• ACT · Acetate ion