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Ligand · TPR

TPR · Tosyl-D-proline

TPR, Tosyl-D-proline (C12 H15 N O4 S, 269.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
TPR
Formula
C12 H15 N O4 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

TPR in 2 structures; the first of them:

  • 1F4E · Crystal structure of E. COLI thymidylate synthase complexed with tosyl-D-proline · TPR A301 · binds ILE55, GLU58, ILE79, TRP80, TYR94, LEU143, CYS146, HIS147 and 4 more
  • 1F4E · Crystal structure of E. COLI thymidylate synthase complexed with tosyl-D-proline · TPR A301 · binds ILE55, GLU58, ILE79, TRP80, TYR94, LEU143, CYS146, HIS147 and 4 more

Residues it binds most

GLY 4, ILE 2, LEU 2, ALA 2, ASN 2, ASP 2, CYS 2, GLN 2, GLU 2, HIS 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • GOL · Glycerol

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