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Ligand · TP4

TP4 · N-[4-[[glutamic acid]-carbonyl]-benzene-sulfonyl-D-prolinyl]-3-amino-propanoic acid

TP4, N-[4-[[glutamic acid]-carbonyl]-benzene-sulfonyl-D-prolinyl]-3-amino-propanoic acid (C20 H25 N3 O10 S, 499.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within…

Component
TP4
Formula
C20 H25 N3 O10 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

TP4 in 2 structures; the first of them:

  • 1F4G · Crystal structure of E. COLI thymidylate synthase complexed with sp-876 · TP4 A601 · binds LYS48, HIS51, SER54, GLU58, ILE79, TRP80, TRP83, LEU143 and 12 more
  • 1F4G · Crystal structure of E. COLI thymidylate synthase complexed with sp- 876 · TP4 A601 · binds LYS48, HIS51, SER54, GLU58, ILE79, TRP80, TRP83, LEU143 and 12 more

Residues it binds most

CYS 4, HIS 4, ILE 4, LEU 4, SER 4, TRP 4, ARG 4, ASN 4, ASP 4, GLU 4 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • GOL · Glycerol

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