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Ligand · TNZ

TNZ · 6-chloranyl-2-methoxy-4-phenyl-quinazoline

TNZ, 6-chloranyl-2-methoxy-4-phenyl-quinazoline (C15 H11 Cl N2 O, 270.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
TNZ
Formula
C15 H11 Cl N2 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

TNZ in 2 structures; the first of them:

  • 7BHS · Crystal structure of MAT2a with quinazoline fragment 2 bound in the allosteric site · TNZ A401 · binds PHE18, PHE20, GLN190, VAL195, GLY273, TRP274, GLY275, ARG313
  • 7BHS · Crystal structure of MAT2A with quinazoline fragment 2 bound in the allosteric site · TNZ A401 · binds PHE18, PHE20, GLN190, VAL195, GLY273, TRP274, GLY275, ARG313

Residues it binds most

GLY 2, PHE 2, ARG 2, GLN 2, TRP 2, VAL 2 (residue and the binding sites it lines).

Found with

  • SAM · S-adenosylmethionine

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